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(For other ways in which men commonly differ physically from women, see man.) During early fetal development, embryos of both sexes appear gender-neutral.

As in cases without two sexes, such as species that reproduce asexually, the gender-neutral appearance is closer to female than to male.

Referring to an unmarried female human as a woman may, in such a culture, imply that she is sexually experienced, which would be an insult to her family.

Most women have the karyotype 46, XX, but around one in a thousand will be 47, XXX, and one in 2500 will be 45, X.

This contrasts with the typical male karotype of 46, XY; thus, the X and Y chromosomes are known as female and male, respectively.

Because humans inherit mitochondrial DNA only from the mother's ovum, genetic studies of the female line tend to focus on mitochondrial DNA.

Whether or not a child is considered female does not always determine whether or not the child later will identify themselves that way (see gender identity).

Later at puberty, estrogen feminizes a young woman, giving her adult sexual characteristics.

An imbalance of maternal hormonal levels and some chemicals (or drugs) may alter the secondary sexual characteristics of fetuses.

In particular, previously common terms such as office girl are no longer widely used.

Conversely, in certain cultures which link family honor with female virginity, the word girl is still used to refer to a never-married woman; in this sense it is used in a fashion roughly analogous to the obsolete English maid or maiden.

Women with typical genetic development are usually capable of giving birth from puberty until menopause.

With regard to gender, a woman may also be a person whose sex assignment does not align with their gender identity, In Old English, wīfmann meant "female human", whereas wēr meant "male human".

Alchemists constructed the symbol from a circle (representing spirit) above an equilateral cross (representing matter).

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